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  1. How and when do I take aspirin? You should take 150mg (2 x75mg tablets) once a day from 12 weeks until 36 weeks of your pregnancy. It is best to take in the evening either with or just after food. Please do not worry if you forget to take a tablet, just take one when you remember, however make sure you only take 150mg once a day.

  2. Low-dose aspirin (81 mg/day) prophylaxis is recommended in women at high risk of preeclampsia and should be initiated between 12 weeks and 28 weeks of gestation (optimally before 16 weeks) and continued daily until delivery.

  3. Taking a low dose of aspirin may help to reduce the risk of: • developing hypertension (high blood pressure) and pre-eclampsia (high blood pressure and excessive protein in your urine) • giving birth to your baby prematurely (before 37 weeks) • your baby being smaller than expected.

  4. There is evidence that taking low-dose aspirin (150mg) every day protects against pre-eclampsia, high blood pressure in pregnancy and improves blood flow to baby so they can continue to grow according to their potential.

  5. ask you to take aspirin for the rest of your pregnancy. Women with one high risk factor or two moderate risk factors should be advised to take 150mg aspirin a day from 12 weeks until birth.

  6. We recommend you take 150mg of Aspirin every night from the 12th week of pregnancy until delivery of your baby. We will ask your GP to provide a prescription for Aspirin and we will continue to monitor your blood pressure and urine protein throughout your pregnancy. Further information

  7. ACOG and SMFM also have provided more detailed information around timing, recommending that low-dose aspirin be initiated between 12 weeks and 28 weeks of gestation (optimally before 16 weeks) and continued daily until delivery 1. USPSTF 2021 Recommendation.

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