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4 Δεκ 2018 · ATP is a major player as a signaling molecule in blood microcirculation. It is released by red blood cells (RBCs) when they are subjected to shear stresses large enough to induce a sufficient shape deformation.
ATP has several known functions in the red blood cell (R BC). It fuels the Na + pump (S achs, 2003; Gusev and Ivanova, 2004), which is thought to be involved in
21 Σεπ 2012 · 1. Introduction. It is known that red blood cells release ATP when blood oxygen tension decreases. ATP has an effect on microvascular endothelial cells to form a retrospective conducted vasodilation to the upstream arteriole.
ATP release by red blood cells (RBCs) under shear stress (SS) plays a pivotal role in endothelial biochemical signaling cascades. The aim of this study is to investigate through numerical simulation how RBC spatiotemporal organization depends on flow and geometrical conditions to generate ATP patterns.
31 Ιουλ 2003 · In whole blood and PRP, ATP and ADP are metabolized to adenosine, 13,15 which is an inhibitor of platelet aggregation. 10,16 It stimulates adenylate cyclase and increases the intracellular level of cAMP, which in turn inhibits calcium mobilization and other signal transduction pathways. We thought it possible that differences in response to ATP ...
8 Σεπ 2009 · We investigate the mechanics and the dynamics of RBCs by a unique noninvasive technique, using weak optical tweezers to measure membrane fluctuation amplitudes with μs temporal and sub nm spatial resolution. This enhanced edge detection method allows to span over >4 orders of magnitude in frequency.
Therefore, we have studied the rates and patterns of catabolism of ATP, ADP, and AMP in whole blood, plasma, and isolated blood cells. Rates of degradation of each nucleotide in cell-free plasma ranged from 0.07-0J2 nmol/min/ml with 1 //.M substrates to 1.1-3.6 nmol/min/ml with 100 /xM substrates.
