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The autoimmune theory of aging, introduced by Roy L. Walford in 1969, asserts that with age, the immune system tends to lose efficiency and experiences widespread dysfunction, evidenced by autoimmunity (immune reactions against one's own body proteins) and a decreased ability to respond to infection and other immune challenges.
1 Μαΐ 2014 · With aging there is a decrease in the immune response, called immunosenescence, concomitantly with the increase in some age-related diseases such as infections, autoimmune disorders, chronic...
22 Οκτ 2023 · The autoimmune theory proposes that the immune system is programmed so that it is no longer able to faultlessly distinguish foreign proteins from the body’s own proteins. If this happens the body’s immune system will attack and destroy its own cells.
1 Ιαν 2022 · Definition. All somatic tissues undergo age-related changes, and the immune system is no exception. However, due to its intimate interactions with all other bodily systems, its aging affects not only immunity itself but may contribute to the emergence of many other age-related pathologies. Overview.
the autoimmune theory that the human body essentially begins to produce autoan- tibodies to its own tissues and or the production of time-acquired deficits primarily in T-cell function predisposes the elderly to the development of infections, chronic
The autoimmune theory proposes that the immune system is programmed so that it is no longer able to faultlessly distinguish foreign proteins from the body’s own proteins. If this happens the body’s immune system will attack and destroy its own cells.
In this chapter, we will review the age-related changes in the immune response and assess the validity of the immune theory of aging (i.e. that these changes in immune response are the primary cause of aging).
