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19 Μαρ 2017 · The first AIDS drug was approved on March 19, 1987—but getting there was by no means easy. Here's the story behind the treatment.
The first HIV drug, zidovudine (also known as Retrovir®, azidothymidine, or AZT), was developed decades before the first known case of HIV. Originally developed to treat cancer, it was a failure against that disease.
In March 1987, AZT became the first drug to gain approval from the U.S. Food and Drug Administration for treating AIDS. AZT, also referred to as zidovudine, belongs to a class of drugs known as nucleoside reverse transcriptase inhibitors, or NRTIs.
27 Αυγ 2009 · Abstract. Within 25 years after zidovudine (3′-azido-2′,3′-dideoxythymidine, AZT) was first described as an inhibitor of HIV replication, 25 anti-HIV drugs have been formally approved for clinical use in the treatment of HIV infections: seven nucleoside reverse transcriptase inhibitors (NRTIs): zidovudine, didanosine, zalcitabine ...
Zidovudine (ZDV), also known as azidothymidine (AZT), was the first antiretroviral medication used to prevent and treat HIV/AIDS. It is generally recommended for use in combination with other antiretrovirals. [ 6 ]
1 Ιουλ 2020 · In 1987, the antiretroviral drug azidothymidine (AZT; now called zidovudine), an inhibitor of the viral reverse transcriptase, was licensed; it provided a temporary reduction in the amount of...
1 Ιαν 2008 · With the outbreak of acquired immunodeficiency syndrome (AIDS), early compounds like Zidovudine (Azidothymidine; AZT) were revisited and later Zidovudine was marketed as the first approved Human...
