Αποτελέσματα Αναζήτησης
20 Μαΐ 2024 · In this study, we combine network toxicology with molecular docking strategies to investigate the potential carcinogenicity of aspartame and its molecular mechanisms of action, with preliminary...
31 Αυγ 2023 · The drinking water exposure produced significant effects (***two-way repeated measures ANOVA, p < 0.0001), suggesting poor performance by the two aspartame groups.
9 Μαΐ 2024 · A detailed evaluation of all unpublished and published studies of aspartame intake, exposures to its metabolites phenylalanine, aspartic acid, and methanol, degradation products, β-aspartame...
14 Ιουλ 2023 · The two bodies conducted independent but complementary reviews to assess the potential carcinogenic hazard and other health risks associated with aspartame consumption. This was the first time that IARC has evaluated aspartame and the third time for JECFA.
10 Δεκ 2013 · Following a thorough review of evidence provided both by animal and human studies, experts have ruled out a potential risk of aspartame causing damage to genes and inducing cancer. EFSA’s experts also concluded that aspartame does not harm the brain, the nervous system or affect behaviour or cognitive function in children or adults.
mechanistic evidence that aspartame exhibits key characteristics of carcinogens, based on consistent and coherent evidence that aspartame induces oxidative stress in experimental systems and suggestive evidence that aspartame induces chronic inflammation and alters cell proliferation, cell death and nutrient supply in experimental systems.
Acute, subacute and chronic toxicity studies with aspartame, and its decomposition products, conducted in mice, rats, hamsters and dogs have consistently found no adverse effect of aspartame with doses up to at least 4000 mg/kg bw/day.
