Αποτελέσματα Αναζήτησης
20 Μαΐ 2024 · The study first constructed an interaction network map of aspartame with gastric cancer targets using network toxicology methods and identified key targets and pathways.
14 Απρ 2021 · Studies on ASs ecotoxicity and possible elimination routes in the environment revealed that negative impacts of ASs are more severe than expected, and the focus should be on the chronic and metabolic toxicities of ASs.
mechanistic evidence that aspartame exhibits key characteristics of carcinogens, based on consistent and coherent evidence that aspartame induces oxidative stress in experimental systems and suggestive evidence that aspartame induces chronic inflammation and alters cell proliferation, cell death and nutrient supply in experimental systems.
31 Αυγ 2023 · Preclinical studies demonstrate that aspartame consumption is associated with neurobehavioral changes including anxiety-like behavior and learning and memory deficits 26,32,33,34,35,36,37.
14 Ιουλ 2023 · The two bodies conducted independent but complementary reviews to assess the potential carcinogenic hazard and other health risks associated with aspartame consumption. This was the first time that IARC has evaluated aspartame and the third time for JECFA.
8 Φεβ 2014 · The gastrointestinal tract hydrolyzes aspartame to aspartyl phenylalanine and methanol. Further hydrolysis of aspartyl phenylalanine to aspartic acid and the essential amino acid, phenylalanine, produces a risk for patients with the homozygous gene for PKU (Rangan and Barceloux 2009).
Acute, subacute and chronic toxicity studies with aspartame, and its decomposition products, conducted in mice, rats, hamsters and dogs have consistently found no adverse effect of aspartame with doses up to at least 4000 mg/kg bw/day.
