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29 Μαΐ 2023 · During the process of looking for new chemical entities, it was found that certain compounds with a basic nucleus of benzoic acid (BA) exhibit a remarkable anticancer potential.
While searching for new bioactive compounds, it has been observed that organic molecules with benzoic acid (BA) moiety possess significant anticancer potential. Several works of literature reported the use of BA from natural or synthetic sources to synthesize bioactive chemicals.
1 Δεκ 2016 · Thus phenolic acids i.e benzoic and cinnamic acid derivatives with higher hydroxyl substitutions could be considered as potential candidates for preventing the cancer cell proliferation. Fig. 4
28 Ιαν 2021 · The purpose of this guideline is to develop recommendations concerning the optimal use of systemic neoadjuvant therapy, including chemotherapy, endocrine therapy, and targeted therapy for patients with invasive breast cancer.
Benzoate was administered at a dose of 250–1500 mg/day for 6 weeks. However, in this study, there was no elevation of D and L-amino acids after this therapy. In addition, catalase levels in the benzoate group showed an increasing trend but not significantly.
3 Φεβ 2020 · This article provides an evidence-based summary to guide practicing oncologists in the assessment, prevention, and management of mucositis induced by chemotherapy, radiotherapy, and targeted therapy.
10 Ιουν 2021 · The estrogen receptor α (ERα) is identified as an effective target for the treatment of ERα+ breast cancer; thus, discovery of novel selective estrogen receptor degraders (SERDs) are developed as an effective method to overcome the resistance of breast cancer.
