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  2. 18 Φεβ 2022 · Serotonin reuptake inhibitor (SRI) medications are well established as first-line pharmacotherapeutic treatment for Obsessive-Compulsive Disorder (OCD). However, despite the excellent safety profile and demonstrated ef-ficacy of these medications, a substantial proportion of individuals with OCD fail to attain sufficient benefit from SRIs.

  3. 1 Ιαν 2023 · Dopamine antagonist treatments remain the best evidenced augmentation strategy for treatment-resistant OCD. Abstract. Serotonin reuptake inhibitor (SRI) medications are well established as first-line pharmacotherapeutic treatment for Obsessive-Compulsive Disorder (OCD).

  4. 22 Δεκ 2012 · For example, while the impact of medications is quite strong for adults in reducing OCD symptoms, current drugs are only somewhat effective for children. In addition, there are unacceptably...

  5. Clomipramine, fluoxetine, fluvoxamine, paroxetine, and sertraline are approved by the U.S. Food and Drug Administration for treatment of OCD. Strong evidence, including from controlled trials, supports using CBT that relies primarily on the behavioral technique of exposure and response prevention (ERP).

  6. 1 Μαΐ 2022 · Highlights. •. This manuscript examines whether or not combination treatment with an SSRI and low intensity psychological treatment (ERP or CBT with or without ERP) is the optimal initial treatment for OCD in comparison to monotherapy treatments (CBT or SSRI). •.

  7. 10 Φεβ 2015 · More recently, glutamate-modulating medications, such as N-acetylcysteine (NAC), memantine, lamotrigine, topiramate, riluzole, and ketamine, have demonstrated evidence of efficacy in patients...

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