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  1. 1 Νοε 2015 · Theories about what causes aging generally fall into one of two groups, genetic or stochastic. Genetic, or programmed theories, propose that aging is genetically determined and organisms have an internal clock that programs longevity.

  2. Modern biological theories of aging in humans fall into two main categories: programmed and damage or error theories. The programmed theories imply that aging follows a biological timetable, perhaps a continuation of the one that regulates childhood growth and development.

  3. 19 Οκτ 2023 · Different rates of aging could occur in different cells or parts of the body because the telomeres in some cells shorten faster than those in other cells. The heterochromatin loss theory suggests that unwinding of chromosomes happens at many areas in a cell.

  4. 1 Νοε 2015 · Here, we review known biological theories of aging and how ROS mechanistically control senescence and the aging process. We also describe the redox-regulated signaling networks controlling the SASP and its important role in driving age-related diseases.

  5. 20 Ιουλ 2022 · Having made substantial progress understanding molecules, cells, genes and pathways, aging biology research is now moving toward integration of these parts, attempting to understand how their ...

  6. 1 Αυγ 2020 · There are many theories of the biological causes of aging, which suggest that many different mechanisms contribute to the aging process. According to Kirkwood, accumulation of random unrepaired molecular damage over time could be the primary cause of cellular aging (Kirkwood, 2005).

  7. This overview describes the historical background and modern versions of selected theories of the mechanisms of biological aging, including the mutation or genome instability theory, the free radical or oxidative stress theory, the mitochondrial theory, the error...