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diagnostic tests.3,4 • Iron studies in anaemia of chronic disease usually show a normal or elevated ferritin level. The serum iron level is often low and TIBC can be low or normal.5 • Iron studies can also be useful in diagnosing conditions of iron overload, including haemochroma - tosis and transfusion-related iron overloading. A high ...
The total iron binding capacity (TIBC) is the amount of available iron binding sites. The transferrin saturation is calculated by dividing the serum iron by the TIBC. Serum iron is a measure of circulating iron, most of which is bound to transferrin.
2 Μαΐ 2024 · The following reference ranges for iron metabolism parameters valuable guidance for assessing iron status and diagnosing related disorders. Iron-binding capacity: 255 to 450 mcg/dL. Transferrin-iron saturation percentage: 25% to 35%.
A TIBC (total iron-binding capacity) test is a blood test that measures your blood’s ability (capacity) to attach (bind) to iron and carry it throughout your body. Healthcare providers use it to help diagnose iron-deficiency anemia and other iron metabolism conditions.
Iron is a key component of haemoglobin in red blood cells, myoglobin in muscle, and many metalloproteins and enzymes. It is essential for uptake of oxygen and its delivery to tissues, utilisation of oxygen by muscle cells, and mitochondrial energy production.3 Normal iron metabolism and regulation is outlined in Figure 1⇓.
Iron is bound to transferrin in the plasma. Total iron binding capacity (TIBC) is a direct measure of level of transferrin.Transferrin levels are reduced in inflammation. Level of transferrin saturation is particularly helpful if assessment of early stages of iron overload with levels > 55% for males and > 50% for females indicative of iron ...
Iron Tests: Normal Range. Patient’s Result. Interpretation. Serum Iron Test: 60-170 mg/dL (10.74-30.43: mmol/L) Transferrin Test: 215-380 mg/dL. Total Iron-Binding: Capacity (TIBC) Test 240-450 mcg/dL Ferritin Blood: Test Adult Males: 24-336 ng/mL: Adult Females: 24-307 ng/mL. Summary. Additional Notes
