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In the Cardiovascular Health Study (CHS) -- a community-based, longitudinal study of the elderly -- cluster analysis was used to characterize patterns of findings on cranial magnetic resonance imaging (MRI) and to define five clusters: Normal, Atrophy, Simple Infarct, Leukoaraiosis, and Complex Infarct. 1 Compared to the other clusters, the ...
11 Μαρ 2024 · Brain age gaps (BAGs) for GM (BAG GM) and WM (BAG WM) were derived from diffusion-weighted imaging and T1 scans separately using 3-dimensional-convolutional neural network deep learning techniques. RESULTS: There was an increase in both BAG GM and BAG WM with raised BP (P <0.05).
31 Μαΐ 2022 · The positive association between MAP and WMLs was greater in women with overweight/obese compared to normal BMI between 56–65 years. Every 10 mmHg increase in MAP above 90 mmHg was associated with a further 0.04% larger WMLs in those with overweight/obesity. Similar effects were not detected in men.
3 Ιουν 2019 · Blood pressure interacts with Alzheimer disease pathology in numerous and unpredictable ways, affecting both β-amyloid and tau deposition, while also interacting with AD genetic risk factors and other metabolic processes.
21 Σεπ 2022 · Considering the overwhelming impact of chronic hypertension on the brain and its vasculature, it is fundamental to identify early biomarkers of disease progression. Advanced brain imaging techniques, discussed below, can provide valuable tools applicable to both human and animal models.
11 Μαρ 2024 · BP was classified into 4 categories: normal BP, high-normal BP, grade 1, and grade 2 hypertension. Brain age gaps (BAGs) for GM (BAG GM) and WM (BAG WM) were derived from diffusion-weighted imaging and T1 scans separately using 3-dimensional-convolutional neural network deep learning techniques.
22 Αυγ 2019 · This chapter describes typical structural brain changes seen on imaging studies in “normal” aging and includes practical guidelines for application in daily clinical neuroradiology practice to identify abnormality.
