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Genetic test results for a mutation linked to breast cancer mean a higher risk of the disease. Learn what positive, negative, and uncertain results mean.
BRCA test results must be reported in a brief and unambiguous way to ensure ease of interpretation. The terms “positive” and “negative” can be ambiguous and should not be used. The report should include details of the laboratory that performed the test along with accreditation numbers (for example, International Organization for ...
Genetic test results show if you have a BRCA1, BRCA2 (BRCA1/2) or other inherited gene mutation related to breast cancer. For some people with breast cancer, test results help guide treatment. There are 3 possible results: Benign or likely benign variant (the test is negative, meaning the results are normal). The test shows normal findings with ...
21 Οκτ 2023 · A positive result means you carry a gene change that increases your risk of cancer. You can work with your healthcare team to manage that risk. A negative result may mean that you don't have the gene change.
Testing for inherited changes in BRCA1 and BRCA2 can give several possible results: a positive result (a harmful change in the gene is present), a negative result (no harmful gene change is present), or a gene change (variant) of uncertain significance (VUS) result. Positive result.
The results of BRCA testing must be interpreted to determine the clinical significance of any variants found during testing. In a diagnostic setting, variant classification forms the basis for clinical decision making. Proper classification of variants is therefore critical to appropriately manage patients.10.
13 Απρ 2022 · BRCA testing looks for abnormal changes in the BRCA1 and BRCA2 genes. A positive test result means you have a higher-than-average risk of developing breast, ovarian and other cancers. Knowing you have a BRCA gene mutation also means you can take steps to lower your risk and help prevent cancer.
