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  1. BRCA1 (BReast CAncer gene 1) and BRCA2 (BReast CAncer gene 2) are genes that produce proteins that help repair damaged DNA. Everyone has two copies of each of these genes—one copy inherited from each parent.

    • Risk Factors

      These are sometimes called protective risk factors, or just...

  2. 5 Αυγ 2020 · BRCA1 and BRCA2 are cancer-susceptibility genes, meaning that people who inherit pathogenic* mutations in either one have an increased risk of developing certain cancers. Hereditary (or “germline”) mutations in BRCA1 or BRCA2 cause Hereditary Breast and Ovarian Cancer Syndrome.

  3. 18 Ιουν 2020 · The breast cancer susceptibility genes known as BRCA1 and BRCA2 are specific genes found in human DNA. Everyone — men and women — inherit BRCA (an abbreviation for breast cancer, often pronounced bracka) genes from their parents.

  4. 6 Ιουν 2024 · People who have a BRCA1 or BRCA2 (BRCA1/2) inherited gene mutation also have an increased risk of pancreatic cancer, prostate cancer (in men) and melanoma (BRCA2 gene mutations only). They also have an increased risk of some second primary cancers (new cancers that develop after breast cancer).

  5. Everyone has two types of breast cancer (“BRCA”) genes in every cell of their body. When functioning properly, BRCA1 and BRCA2 repair DNA, keep other genes healthy, and prevent cancerous changes in the cells. When a mutation damages either of these genes, the person’s risk of cancer increases.

  6. Evidence-based, expert-reviewed summary about the BRCA1 and BRCA2 genes and hereditary breast and ovarian cancer. This summary also contains information about the cancer risks associated with BRCA1/BRCA2, screening, risk-reduction, treatment, and prognosis.

  7. faulty genes are the underlying cause for about 5–10% (5 to 10 in 100) of breast cancers. There are two genes that, if mutated, greatly increase an individual’s chance of developing breast and ovarian cancer. These are known as the BRCA1 (Breast Cancer 1) and BRCA2 (Breast Cancer 2) genes. These two genes account for approximately

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