Αποτελέσματα Αναζήτησης
A positive test result indicates that a person has a harmful change in BRCA1 or BRCA2 (these are typically called “pathogenic” or “likely pathogenic” variants on laboratory test reports) and has an increased risk of developing certain cancers.
- Genetic Testing Fact Sheet
Genetic testing can give several possible results: positive,...
- Risk Factors
But research has shown that certain risk factors may...
- Genetic Testing Fact Sheet
18 Ιουν 2020 · The breast cancer susceptibility genes known as BRCA1 and BRCA2 are specific genes found in human DNA. Everyone — men and women — inherit BRCA (an abbreviation for breast cancer, often pronounced bracka) genes from their parents.
5 Αυγ 2020 · BRCA1 and BRCA2 are cancer-susceptibility genes, meaning that people who inherit pathogenic* mutations in either one have an increased risk of developing certain cancers. Hereditary (or “germline”) mutations in BRCA1 or BRCA2 cause Hereditary Breast and Ovarian Cancer Syndrome.
21 Οκτ 2023 · The BRCA gene test looks for changes in the BRCA1 and BRCA2 genes. Other genes also can increase the risk of breast and ovarian cancer. Some genetic tests look for these other genes in addition to the BRCA genes. A genetic test that looks at many different genes is called a multigene panel test.
6 Ιουν 2024 · Women who have a BRCA1 or BRCA2 (BRCA1/2) inherited gene mutation have an increased risk of breast cancer and ovarian cancer. Estimates of these risks vary greatly. Women who have a BRCA1/2 inherited gene mutation have more than a 60% chance of getting breast cancer in their lifetimes and a 10%-60% chance of getting ovarian cancer [2].
Everyone has two types of breast cancer (“BRCA”) genes in every cell of their body. When functioning properly, BRCA1 and BRCA2 repair DNA, keep other genes healthy, and prevent cancerous changes in the cells. When a mutation damages either of these genes, the person’s risk of cancer increases.
BRCA is an abbreviation for breast cancer gene. BRCA1 and BRCA2 are two genes that can increase someone's chances of developing cancer if they mutate.
