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BRCA1 (BReast CAncer gene 1) and BRCA2 (BReast CAncer gene 2) are genes that produce proteins that help repair damaged DNA. Everyone has two copies of each of these genes—one copy inherited from each parent.
- Genetic Testing Fact Sheet
Genetic testing can give several possible results: positive,...
- Risk Factors
It is usually not possible to know exactly why one person...
- Genetic Testing Fact Sheet
BRCA1 and BRCA2 are genes involved in DNA repair. Constitutional (germline) pathogenic variants in these genes are associated with hereditary breast and ovarian cancer, as well as other cancers.
23 Ιουλ 2023 · Breast cancer genes BRCA1 and BRCA2 are tumor suppressor genes whose mutations significantly increase the likelihood of developing particular types of epithelial malignancies, namely breast and ovarian cancer.
18 Ιουν 2020 · The breast cancer susceptibility genes known as BRCA1 and BRCA2 are specific genes found in human DNA. Everyone — men and women — inherit BRCA (an abbreviation for breast cancer, often pronounced bracka) genes from their parents.
23 Δεκ 2011 · BRCA1 and BRCA2 are tumour suppressor genes, the coding regions of which show no homology to previously described proteins or to each other. If one copy of either gene is mutated in the germ...
18 Ιουλ 2020 · BRCA1 and BRCA2 are the genes related with breast and ovarian cancer. They have function in DNA repair processes and thus they are tumor suppressor genes. There are hundreds of mutations identified in these genes.
7 Νοε 2013 · BRCA1 and BRCA2 gene mutations comprise the most important genetic susceptibility of BC. Except for few common mutations, the spectrum of BRCA1 and BRCA2 mutations is heterogeneous in diverse populations. 185AGdel and 5382insC are the most important BRCA1 and BRCA2 alterations which have been encountered in most of the populations.
