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  1. The Veterinarian’s Guide to Accidental Rodenticide Ingestion by Dogs and Cats focuses on anticoagulants. This addendum is intended to help veterinarians recognize and treat the symptoms of bromethalin toxicity in domestic animals.

  2. Cats demonstrate a similar clinical course to dogs, but are much more sensitive to bromethalin. The LD 50 in cats is 0.54 mg/kg.4 Cats may also demonstrate ileus and resultant abdominal distention.1,5 Range of Dosages The dosages cited for dogs and cats are medians, and any individual patient may be more sensitive to the effects of bromethalin.

  3. In dogs, the LD50 of bromethalin is 2.38-3.65 mg/kg, with a minimum lethal dose being 2.5 mg/kg.1 Cats are more sensitive to the effects of bromethalin, and the LD50 is significantly lower (0.54 mg/kg).1 Clinical signs are dose-dependent, and the onset of clinical signs depends on the amount ingested. Typically, with acute ingestion, signs may ...

  4. Bromadiolone is an anticoagulant that works by inhibiting the blood's ability to clot, leading to internal bleeding and eventual death. On the other hand, Bromethalin is a neurotoxin that affects the central nervous system, causing paralysis and ultimately death.

  5. The median lethal dose (LD 50) may vary in the literature; however, toxic doses are widely accepted at one-tenth of the lowest reported LD 50 in companion animal species. Cats tend to be exquisitely sensitive, with an LD 50 of 0.4–0.71 mg/kg; dogs are moderately sensitive, with an LD 50 of 2.38–5.6 mg/kg; and guinea pigs are uniquely ...

  6. 21 Μαρ 2024 · Compared to other types of rodent poisons, the chance of a cat eating a toxic dose of bromethalin by consuming a single dead rodent is significantly lower. The only way it’s likely for a cat to experience relay toxicosis with bromethalin is when the cat habitually eats poisoned rodents over time.

  7. 1 Οκτ 2008 · Bromethalin is one of the lesser known rodenticides on the market, and poisoning in dogs and cats is most likely underreported. Minimum toxic/lethal dose of the bait is approximately 16-25 g/kg BW in dogs and 4.5 g/kg BW in cats. Relay toxicosis may be a concern in cats who are excellent mousers.