Αποτελέσματα Αναζήτησης
Therefore, reduction of circulating ionized calcium by an upregulation of the parathyroid CaSR following burns could potentially dampen or curtail the systemic inflammatory response, while the increase in inflammatory-site calcium may stimulate the inflammasome also via the parathyroid CaSR.
1 Αυγ 2018 · The liberation of calcium and possibly phosphorus and magnesium by bone resorption may sustain and intensify the inflammatory response.
17 Νοε 2022 · The present review aims to elucidate and clarify the emerging regulatory effects that the CaSR plays in inflammation in several tissues, where it mostly promotes pro-inflammatory responses, with the exception of the large intestine, where contradictory roles have been recently reported.
1 Μαρ 2020 · In this review, we discuss how calcium signaling pathways in endothelial cells play an essential role in affecting barrier function and facilitating inflammation. Inflammatory mediators, such as thrombin and histamine, increase intracellular calcium levels.
5 Ιουν 2023 · We show that in both human and mouse macrophages, reduced mCa 2+ uptake amplifies cytosolic Ca 2+ oscillations and potentiates downstream nuclear factor kappa B activation, which is central to...
20 Ιουν 2019 · In the present review, we elaborate on the physiological significance of these negative feedback regulators of calcium absorption, and provide evidence to show how our body can efficiently restrict a flood of calcium influx in order to maintain calcium homeostasis.
5 Ιαν 2021 · Gastrointestinal mechanisms in inflammatory auto-immune disease that impact nutritional state and nutrient absorption have also been implicated. We will touch on the effects of calcium and vitamin D on bone health, as well as introduce the Gut-Bone Axis concept that has gained significant attention in recent years.
