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Abstract: This article provides an update on the global cancer burden using the GLOBOCAN 2020 estimates of cancer incidence and mortality produced by the International Agency for Research on Cancer. Worldwide, an estimated 19.3 million new cancer cases (18.1 million excluding nonmelanoma skin cancer) and almost 10.0 million cancer deaths (9.9 ...
4 Απρ 2024 · INTRODUCTION. Cancer is a major societal, public health, and economic problem in the 21st century, responsible for almost one in six deaths (16.8%) and one in four deaths (22.8%) from noncommunicable diseases (NCDs) worldwide.
The IARC estimates, based on the best sources of data available in countries in 2022, highlight the growing burden of cancer, the disproportionate impact on underserved populations, and the urgent need to address cancer inequities worldwide. In 2022, there were an estimated 20 million new cancer cases and 9.7 million deaths.
The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk–outcome pairs were included on the basis of the World Cancer Research Fund criteria.
Cancer is a major disease burden worldwide but there are marked geographical variations in incidence overall and at specific organ sites. Reliable estimation of the number of new cases (incidence) requires population-based cancer registra-tion.
The global increase in cancer burden is projected to fall most heavily on low- and middle-income countries. Cancer inequalities within countries. Socioeconomic gradients in cancer incidence vary in magnitude and direction by cancer site.
Risk-attributable cancer burden varied by world region and Socio-demographic Index (SDI), with smoking, unsafe sex, and alcohol use being the three leading risk factors for risk-attributable cancer DALYs in low SDI locations in 2019, whereas DALYs in high SDI locations mirrored the top three global risk factor rankings.
