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Chemotherapy, the primary choice for treatment of cancer, is often ineffective or/and presents itself with many debilitating side effects, including loss of appetite, nausea, insomnia, and anxiety. Components of cannabis extracts, including cannabinoids and terpenes, may present an alternative for controlling side effects and may be used for ...
- Molecular Mechanism of Cannabinoids in Cancer Progression
The treatment of CBD/THC in combination with other...
- Molecular Mechanism of Cannabinoids in Cancer Progression
11 Μαρ 2022 · Drugs that target the endocannabinoid system are of interest as pharmacological options to combat cancer and to improve the life quality of cancer patients. From this perspective,...
The treatment of CBD/THC in combination with other chemotherapeutic drugs acts in a synergic way, suggesting their use in combinatory therapy in several types of human cancers. A poor prognosis of breast cancer is correlated with high levels of metalloproteases.
Results from these studies are essential to clarify whether cannabinoids could be helpful in cancer treatment. An interesting idea is their synergistic interaction with some conventional cytostatic drugs as well as their capacity to suppress metastasis and angiogenesis.
7 Αυγ 2024 · Triple-negative breast cancer (TNBC) accounts for about 10-20% of all breast cancer cases and is associated with an unfavorable prognosis. Until recently, treatment options for TNBC were limited to chemotherapy.
27 Νοε 2021 · Abstract. Plant-based, synthetic, and endogenous cannabinoids have been shown to control a diverse array of biological processes, including regulation of cell fate across cancers. Their promise as broad-based antitumor agents in preclinical models has led to the initiation of pilot clinical trials.
15 Ιαν 2008 · In particular, emerging evidence suggests that agonists of cannabinoid receptors expressed by tumor cells may offer a novel strategy to treat cancer. Here, we review recent work that raises interest in the development and exploration of potent, nontoxic, and nonhabit forming cannabinoids for cancer therapy.