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Recent reviews show that an increased ratio of omega-6 to omega-3 fatty acids contributes to obesity rates by increasing levels of the endocannabinoid signals AEA and 2-AG, overstimulating CB 1 R and leading to increased caloric intake, reduced metabolic rates, and weight gain.
4 Ιουν 2024 · The endocannabinoid system (ECS) is a neuromodulatory signaling system, present along the entire gut-brain axis, that plays a critical role in central and peripheral regulation of food intake and...
5 Αυγ 2020 · The anorexia/cachexia syndrome is the result of weight loss (caused by changes in taste, lack of hunger) and increased energy metabolism; cannabis use has been associated with an increase in appetite and weight gain, leading to examination of its therapeutic effect on cancer and HIV-associated anorexia/cachexia.
10 Σεπ 2018 · The conversion of white in beige adipose tissue is a potential new therapeutic target for obesity. Cannabinoid receptors (CB) regulate thermogenesis, food intake and inflammation. CB1 ablation or inhibition helps reducing body weight and food intake.
1 Μαΐ 2013 · Similarly, in humans, cannabis-derivatives appear useful treatments for anorexia and weight loss associated with Human Immunodeficiency Virus infection [5], [6], whereas Rimonabant was effective for the treatment of obesity, but was withdrawn because of safety concerns [7].
For older adults, generally, the available evidence suggests cannabis use may be associated with greater frequencies of mental health issues, substance use, and acute healthcare use, and the benefit-to-risk ratio is unclear.
7 Νοε 2023 · Results. In general, cannabis use reduced weight by 1.87 kg (95% CI: −3.71 to −0.03) and WC (mean difference = −2.19, 95% CI: −4.44 to 0.06). When examining subgroups, longer follow-up periods...
