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  1. 1 Μαΐ 2024 · Previous observational studies have established a clear link between negative emotions – including anger, anxiety and sadness – and an increased risk for heart attacks and strokes. But little is known about how these emotions trigger changes in the body that lead to cardiovascular events.

  2. 6 Αυγ 2022 · Several cohort studies have indicated that anger (higher anger expression, frequent episodes of anger, or trait anger) is linked to higher risk of total CVD, 5 atrial fibrillation (AF), 6 coronary heart disease (CHD), 7, 8 heart failure (HF), 9 and CVD mortality, 10 but other cohort studies and meta-analyses showed no such associations 11, 12 ...

  3. 4 Μαρ 2014 · Outbursts of anger may trigger heart attacks, strokes and other cardiovascular problems in the two hours immediately afterwards, according to the first study to systematically evaluate previous research into the link between the extreme emotion and all cardiovascular outcomes.

  4. Observational studies have associated anger with increased risks of myocardial infarction—heart attack—and stroke, but little has been known about the mechanism behind this phenomenon. Now, the results of a randomized clinical trial published in the Journal of the American Heart Association suggest that anger may affect blood vessel ...

  5. 3 Μαρ 2014 · We performed a systematic review of studies evaluating whether outbursts of anger are associated with the short-term risk of heart attacks, strokes, and disturbances in cardiac rhythm that occur in everyday life.

  6. 3 Δεκ 2015 · Defective NOTCH signaling has been shown to cause various cardiac pathologies including Alagille syndrome (AGS), 39,40 BAV 41 , and LVNC 4 . We suggest that these pathologies result from the disruption of the NOTCH-mediated communication between the endocardium and the surrounding cardiac tissues.

  7. 4 Οκτ 2018 · Studies of Notch function in cardiac development have examined the role of individual pathway components by means of conditional gene inactivation and activation approaches in specific cell...

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