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30 Ιαν 2020 · The main mechanisms that cause increased serum liver enzymes are cell damage and the induction of enzyme synthesis. The enzymes are mainly found in the hepatocyte mitochondria, cytoplasm, or cell membrane. Where enzymes are elevated due to cell damage, the leaking of enzymes depends on their concentration and location within the cell.
Increased liver enzyme activities are common results in small animal practice and can suggest patterns of liver disease, including hepatocellular damage, cholestasis, or both. Liver enzymes, especially ALP, are not specific for primary liver disease.
Here are some common causes of bone fragments in dog poop: Intentional Feeding: Some dog owners intentionally give bones to their pets as a treat or to satisfy their chewing needs. While this practice can provide entertainment for the dog, it can also result in bone fragments being passed in their stool.
Usually an elevation in ALP is due to hepatic or bone isoenzymes. However, exogenous and endogenous glucocorticoids can induce a specific isoenzyme and thus result in elevated serum levels in the dog (but not in the cat).
7 Σεπ 2024 · Elevated liver enzymes in dogs can be caused by a variety of conditions, both within and outside the liver. The most common causes of elevated liver enzymes in dogs are due to medications like prednisone, Cushing's disease, liver inflammation such as hepatitis, and benign, age-related changes.
Although some dogs may show no signs, typical signs include loss of appetite, excessive thirst and urination, fever, vomiting, jaundice, and an enlarged liver. Affected animals may collapse and have pale mucous membranes due to rupture of the liver and subsequent internal bleeding.
enzymes have leaked out of the liver cells due to cell damage. AST is found in muscle cells as well as liver cells, so an elevation in AST without a similar elevation in ALT may indicate muscle damage rather than liver damage.
