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Blood urea nitrogen (BUN): Elevated BUN levels indicate impaired kidney function. Serum creatinine: Increased creatinine levels suggest reduced kidney function. Symmetric dimethylarginine (SDMA): SDMA is a more sensitive and specific marker for kidney disease compared to traditional markers like BUN and creatinine.
5 Μαΐ 2005 · When a laboratory test performed on your dog’s blood shows elevated blood urea nitrogen (BUN) and creatinine levels that indicate kidney problems, the most likely cause is: A) chronic renal failure (CRF) B) a bacterial infection. C) a tick-borne disease. D) an endocrine imbalance. E) a urinary tract infection. If you guessed A, you’re not alone.
3 Ιαν 2024 · High levels of BUN (blood urea nitrogen) and creatinine in dogs can indicate a problem with their kidneys. Luckily, there are steps you can take to help lower these levels and support your dog’s kidney health.
29 Ιουν 2023 · What Causes Kidney Disease in Dogs? Dr. Klein warns that kidney disease could be caused by a lot of things, including infection (such as with the bacteria that causes leptospirosis), trauma...
Glomerular filtration rate (GFR) is the gold standard measurement of renal function; however, its measurement is rarely indicated in patients with CKD. Creatinine and, to a lesser extent, BUN are correlated with GFR, but, as noted earlier, GFR must be reduced by 75% before azotemia is seen.
A dog can lose up to 75% of kidney function before showing any changes in renal blood values such as elevated BUN and creatinine levels. Therefore, these traditional diagnostic methods could detect kidney failure only after a significant loss of function, making early intervention difficult.
A dog in compensated chronic kidney failure with marginal kidney function may have normal levels of BUN and creatinine but will have a low urine specific gravity. If a major stress such as illness or surgery occurs, the kidneys may fail, sending the blood test values up quickly.
