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But taking into account CDP's 3-day half life and the 18.5% choline content of CDP, how much choline will this consistently yield after accumulation?
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If you look at that study (CDP-choline increases plasma ACTH and potentiates the stimulated release of GH, TSH and LH: the cholinergic involvement), they injected CDP-choline directly into the ventricular system of the brain.
My understanding is that CDP Choline has a very long half life so the amount builds up in your system. The first time I used it, it worked great for a few weeks, and then it started affecting my sleep. And then I started to link the depression I was feeling with the CDP choline. Alpha GPC has a much lower half life so I'm trying that now.
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Cytidine 5′‐diphosphocholine (CDP‐choline or citicoline) is a highly bioavailable compound with potential benefits for aiding neural repair and increasing acetylcholine levels in the central and peripheral nervous system.
Structures and localization of the enzymes in the CDP-choline pathway. [1]: 415 The CDP-choline pathway, first identified by Eugene P. Kennedy in 1956, is the predominant mechanism by which mammalian cells synthesize phosphatidylcholine (PC) for incorporation into membranes or lipid-derived signalling molecules. [1] [2] The CDP-choline pathway represents one half of what is known as the ...
5 Ιουν 2021 · Citicoline / CDP-Choline (Jarrow 250 mg) - This has been a game changer for me personally. There have been studies on citicholine use for fighting cocaine addiction (checkout how similar porn addiction is). It helps in repairing the damaged dopamine receptors. Effects noticed - No tension-type headache anymore.
