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  1. Posterior fossa decompression successful in treating central apnea in some patients; some will require ventilation, often noninvasive ... Congenital central hypoventilation syndrome (CCHS) is a rare, lifelong condition that causes primary alveolar hypoventilation. ... Finsterer J. Leigh and Leigh-like syndrome in children and adults. Pediatr ...

  2. 25 Μαΐ 2017 · Diaphragmatic pacing and positive airway pressure (PAP) modalities continue to be used for treatment of certain hypoventilation syndromes. The best and most widely tested and efficient treatments for hypoventilation remain positive airway pressure therapy.

  3. The treatment of hypoventilation primarily is directed at correcting the underlying disorder. Use caution when correcting chronic hypercapnia. Rapid correction of the hypercapnia can alkalinize...

  4. Central alveolar hypoventilation disorders denote conditions resulting from underlying neurologic disorders affecting the sensors, the central controller, or the integration of the signals. Such disorders can lead to insufficient ventilation and an increase in PaCO 2 (hypercarbia), as well as a decrease in PaO 2 (hypoxemia).

  5. 11 Ιουλ 2024 · Treatment involves nocturnal ventilation, including the use of invasive ventilation. Definition Alveolar hypoventilation, defined as an elevation in PaCO₂ to levels >45 mmHg, can occur with several disorders: obesity hypoventilation syndrome, restrictive thoracic disorders, central sleep apnea syndromes, and COPD. [1]

  6. 21 Σεπ 2020 · Congenital Central Hypoventilation Syndrome (CCHS) is a rare condition characterized by an alveolar hypoventilation due to a deficient autonomic central control of ventilation and a global autonomic dysfunction. Paired-like homeobox 2B (PHOX2B) mutations are found in most of the patients with CCHS.

  7. The commonest causes of hypoventilation in adults include COPD, obesity hypoventilation syndrome (OHS), neuromuscular disease (NMD), and chest wall deformity. Congenital Central hypoventilation disease (CCHS) is a rare disease usually manifested in neonates but it is reported to occur in adults in a milder form, it is usually associated with ...

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