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1. www.nature.com › articles › s41434/023/00390-5Successes and challenges in clinical gene therapy | Gene Therapy...

   www.nature.com › articles › s41434/023/00390-5

   8 Νοε 2023 · In this article, we highlight success and ongoing challenges in three areas of high activity in gene therapy: inherited blood cell diseases by targeting hematopoietic stem cells, malignant...

   • Gene therapy and gene correction: targets, progress, and challenges for ...

     Challenges to gene therapy. One of the most important issues...

2. www.researchgate.net › publication › 329250849_Gene_therapy_A_comprehensive_review(PDF) Gene therapy: A comprehensive review - ResearchGate

   www.researchgate.net › publication › 329250849_Gene_therapy_A_comprehensive_review

   1 Δεκ 2018 · This review focuses on the application of gene therapy for the correction of inherited diseases, the limitations and drawbacks encountered in some of the early clinical trials and the revival...

3. www.researchgate.net › publication › 380396422_Gene_therapy_principles_challenges(PDF) Gene therapy: principles, challenges and use in ... -...

   www.researchgate.net › publication › 380396422_Gene_therapy_principles_challenges

   7 Μαΐ 2024 · Important safety concerns include immune reactions to the vector, the foreign DNA or the new protein resulting from gene therapy, and a remaining low cancer risk based on insertional...

4. www.researchgate.net › publication › 375487634_Successes_and_challenges_in(PDF) Successes and challenges in clinical gene therapy -...

   www.researchgate.net › publication › 375487634_Successes_and_challenges_in

   8 Νοε 2023 · In this article, we highlight success and ongoing challenges in three areas of high activity in gene therapy: inherited blood cell diseases by targeting hematopoietic stem cells, malignant...

5. link.springer.com › article › 10Gene therapy: principles, challenges and use in clinical practice

   link.springer.com › article › 10

   • Αποθηκευμένο αντίγραφο

   7 Μαΐ 2024 · To address this knowledge gap, this review summarizes core principles, benefits, potential risks and challenges of gene therapy, with a particular focus on hemophilia and spinal muscular atrophy, and discusses future perspectives.

6. www.semanticscholar.org › paper › Successes-and-challenges-in-clinical-gene[PDF] Successes and challenges in clinical gene therapy -...

   www.semanticscholar.org › paper › Successes-and-challenges-in-clinical-gene

   1 Νοε 2023 · In this article, we highlight success and ongoing challenges in three areas of high activity in gene therapy: inherited blood cell diseases by targeting hematopoietic stem cells, malignant disorders using immune effector cells genetically modified with chimeric antigen receptors, and ophthalmologic, neurologic, and coagulation disorders using ...

7. www.nature.com › articles › s41434/020/00197-8Gene therapy and gene correction: targets, progress, and...

   www.nature.com › articles › s41434/020/00197-8

   Challenges to gene therapy. One of the most important issues regarding gene therapy is safety. Gene therapy research took a step backward in 1999 following the death of Jesse...