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  1. 8 Νοε 2023 · In this article, we highlight success and ongoing challenges in three areas of high activity in gene therapy: inherited blood cell diseases by targeting hematopoietic stem cells, malignant...

  2. 8 Σεπ 2024 · This achievement marked a historic moment as Glybera became the first gene therapy treatment to be authorized in Europe, setting a precedent for future gene-based therapies. 19 Nonetheless, despite its groundbreaking status, Glybera® faced challenges related to its cost-effectiveness. With a staggering price tag exceeding €1 million per ...

  3. 9 Οκτ 2020 · Gene therapy and gene correction techniques have developed rapidly over the last several decades, aimed at treating genetic diseases for which current treatment options are limited or...

  4. 1 Ιουν 2022 · Introduction. The first individual to receive gene-modified cells under an approved clinical trial was treated in 1989. 1 Now, over three decades later, we see the promise of genetic therapies becoming a reality for individuals suffering from life-limiting illnesses.

  5. 30 Ιουν 2018 · In the present manuscript, we review the recent advances made in gene therapy for ovarian cancer, highlighting the latest clinical trials experience, the current challenges and future perspectives. Keywords: ovarian cancer, gene therapy, delivery systems, promoter, suicide genes, ovarian cancer stem cells. 1.

  6. 10 Μαρ 2020 · While somatic gene therapy can be considered gender-neutral, germ therapy, insofar as it impacts on reproductive choices, can be gender-relevant.

  7. 24 Αυγ 2022 · This review discusses in detail the current challenges surrounding the practice of gene therapy, focusing on the moral arguments and scientific claims that affect the advancement of the technology. The review also suggests precautionary principles as a means to navigate ethical uncertainties.

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