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Chelation therapy is a process in which a substance is delivered intravenously (through the veins) to bind metals or minerals so they can be removed from the body via urination. When it’s used as a complementary treatment for heart disease, a course of treatment can require 20 to 40 weekly infusions lasting several hours each.
1 Μαρ 2022 · EDTA is an intravenous chelating agent with high affinity to divalent cations (lead, cadmium, and calcium) that may be beneficial in the treatment of cardiovascular disease (CVD). Although a large randomized clinical trial showed benefit, smaller studies were inconsistent.
Key findings. Twenty-four studies (15 prospective studies, 5 retrospective case series, 4 randomized clinical trials) assessed repeated ethylenediaminetetra-acetic acid (EDTA) chelation treatment in patients with preexistent cardiovascular disease.
Chelation therapy, defined as repeated intravenous administration of ethylenediamine tetraacetic acid (EDTA) with or without vitamins, trace elements, or iron supplements for the treatment of CHD. Studies with or without control groups were included.
24 Απρ 2015 · Chelation therapy remains controversial, but the best evidence to date, TACT, a randomized, placebo-controlled comparison of chelation and placebo infusion therapy, suggests that chelation therapy reduced CVD events by 18% with marked reduction in the diabetic population by 41%.
26 Μαΐ 2015 · The landscape for chelation therapy has changed, and environmental toxins may emerge as a modifiable risk factor for heart disease. The US Food and Drug Administration reviewed the TACT in a positive light but encouraged us to carry out another study to confirm these results (TACT2 is being planned).
The off-label use of chelation therapy (disodium edetate or EDTA) for prevention of cardiovascular disease (CVD) is widespread, despite the lack of convincing evidence for efficacy or approval from the Food and Drug Administration.
