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  1. 8 Απρ 2019 · Pyruvate is generated by two primary methods – through the glycolytic pathway, and through the metabolism of amino acids. While proteins supply nearly 10% of the body’s energy needs, only some amino acids are channeled through pyruvate into the cellular respiratory machinery.

  2. How pyruvate from glycolysis is converted to acetyl CoA so it can enter the citric acid cycle. Pyruvate is modified by removal of a carboxyl group followed by oxidation, and then attached to Coenzyme A.

  3. 18 Δεκ 2021 · In eukaryotic cells, the pyruvate molecules produced at the end of glycolysis are transported into mitochondria, which are the sites of cellular respiration. There, pyruvate will be transformed into an acetyl group that will be picked up and activated by a carrier compound called coenzyme A (CoA).

  4. Cellular respiration occurs in the cells of all living things, both autotrophs and heterotrophs. All of them catabolize glucose to form ATP. The reactions of cellular respiration can be grouped into three main stages and an intermediate stage: glycolysis , Transformation of pyruvate , the Krebs cycle (also called the citric acid cycle), and ...

  5. Pyruvate’s primary function in cellular respiration is to serve as a substrate for the citric acid cycle, also known as the Krebs cycle. During this cycle, pyruvate is transported into the mitochondria, where it undergoes further oxidation to produce additional ATP molecules.

  6. In eukaryotic cells, the pyruvate molecules produced at the end of glycolysis are transported into mitochondria (Figure \(\PageIndex{1}\)), which are the sites of cellular respiration. In order for pyruvate, the product of glycolysis, to enter the next pathway, it must undergo several changes.

  7. In the next stage of cellular respiration—and in the presence of oxygen—pyruvate produced in glycolysis is transformed into an acetyl group attached to a carrier molecule of coenzyme A. The resulting acetyl CoA is usually delivered from the cytoplasm to the mitochondria, a process that uses some ATP.

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