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3 Ιουλ 2023 · This activity outlines the indications, action, and contraindications for Chloramphenicol as a valuable agent in the treatment of superficial eye infections, otitis externa, Typhoid fever, and other severe life-threatening conditions, especially those caused by Haemophilus influenza.
However, due to its severe toxicity, chloramphenicol is no longer used as the first medication of choice in most countries with access to safer antibiotics; instead, this medication is typically used when other antibiotics are ineffective or contraindicated.
Clinical Notes: Contra-indications. acute porphyria. Blood dyscrasias and patients taking medicines liable to suppress bone marrow. pregnancy and breast feeding. Avoid repeated courses . Pharmacokinetics:
Contra-indications. acute porphyria. previous history of sensitivity or toxic reaction to chloramphenicol. blood dyscrasias and patients taking medicines liable to suppress bone marrow. pregnancy and breast feeding. Avoid repeated courses.
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View chloramphenicol information, including dose, uses, side-effects, renal impairment, pregnancy, breast feeding, contra-indications and monitoring requirements.
Chloramphenicol should not be used topically because small amounts may be absorbed and, rarely, cause aplastic anemia. Hypersensitivity reactions are uncommon. Optic and peripheral neuritis may occur with prolonged use.
