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9 Ιαν 2020 · They are almost invariably associated with chronic gastritis, which may eventually lead to a loss of mucosal glands. This atrophic change usually predominates in the antrum and may spread proximally. Most patients with atrophic gastritis also develop gastric intestinal metaplasia (GIM).
3 Ιαν 2022 · Intestinal metaplasia is a cellular change in the lining of the stomach or esophagus that resembles the intestines. It can be a precursor to cancer and is often caused by chronic inflammation, infection or acid reflux.
24 Απρ 2024 · Gastric intestinal metaplasia (GIM) is an intermediate precancerous gastric lesion in the gastric cancer cascade of chronic gastritis, atrophic gastritis, intestinal metaplasia (IM), dysplasia, and adenocarcinoma [2]. Although the risk of gastric cancer is increased in patients with GIM, the absolute risk is modest.
13 Μαρ 2020 · Gastric intestinal metaplasia (GIM) is precancerous with a worldwide prevalence of 25%. Eradicating Helicobacter pylori prevented about half of gastric cancers; failure to prevent the rest was attributed to GIM. GIM is irreversible and often extensive. There is no treatment.
6 Δεκ 2019 · Guideline recommendations for the management of patients with gastric intestinal metaplasia (GIM) detected as part of routine upper endoscopy for reasons including work up of endoscopically identified gastropathy/presumed gastritis, dyspepsia or exclusion of Helicobacter pylori (H. pylori).
15 Φεβ 2019 · Gastric intestinal metaplasia (GIM) is a premalignant condition that can lead to intestinal-type gastric adenocarcinoma. It is characterized by a change in the gastric mucosa to a small-intestinal phenotype. Infection with Helicobacter pylori is the most common factor associated with GIM.
1 Νοε 2021 · Endoscopic ablation therapies have shown promise for invisible or extensive dysplasia. Summary: Endoscopic resection is appropriate for visible dysplasia and early-stage GAC without high-risk features that persists despite H. pylori eradication therapy.
