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Therefore, the focus in this lecture is PLE in animals with chronic GI disease. The major causes of PLE in adult dogs tend to be intestinal lymphangiectasia, inflammatory bowel disease (IBD), alimentary tract lymphoma (LSA), and fungal infections (i.e., histoplasmosis and pythiosis).
Protein-losing enteropathy (PLE) is not a specific disease, but is described as a group of diseases that cause the loss of proteins from the bloodstream into the gastrointestinal (GI) tract. Primary GI disease, heart disease, and diseases of the lymphatic system can all cause PLE.
1 Μαΐ 2011 · The major causes of PLE in juvenile dogs tend to be parasites and chronic intussusception. Cats with PLE usually have IBD or alimentary tract lymphoma. Many dogs with PLE have hypocholesterolemia. Pets with protein-losing nephropathies usually have hypercholesterolemia, while those with hepatic insufficiency often have hypocholesterolemia.
major causes of protein-losing enteropathy in adult dogs tend to be intestinal lymphangiectasia, alimentary tract lymphoma (LSA), intestinal fungal infections (i.e., histoplasmosis and pythiosis), and severe inflammatory bowel disease (IBD.
Causes of PLE. Any GI disease can cause PLE if it is severe enough. Chronic GI diseases that may cause PLE include inflammatory bowel disease (IBD), neoplasia (particularly lymphoma), lymphangiectasia, histoplasmosis, GI parasites, and pythiosis.
Key points. Protein-losing enteropathies (PLE) cause enteric protein loss, principally albumin, and most often reflect small intestinal disease. Clinical signs of PLE usually result from intestinal dysfunction (vomiting, diarrhea, weight loss) and/or hypoalbuminemia (body cavity effusion, peripheral edema).
30 Σεπ 2015 · Causes of Low Blood Albumin in Dogs. Hypoalbuminemia can result as a decrease in the ingestion of protein, a loss of protein through the gut or kidney, or by a failure of the liver to produce protein (therefore causing blood albumin levels to decline).
