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Side Effects When taken by mouth : Citicoline is possibly safe when used for up to 12 weeks. Side effects might include stomach pain , back pain, blurred vision , constipation , and...
An impressive example is the median lethal dose (LD 50) of an acute single intravenous application of citicoline, which equals 4,600 and 4,150 mg/kg in mice and rats, respectively. The LD 50 for ingested citicoline is even higher at approximately 8 g/kg in both mice and rats.
28 Ιουλ 2012 · The primary objective of this study was to assess the effects of citicoline compared with placebo on the recovery of patients with moderate-to-severe acute ischaemic stroke at 3 months, after having received 2000 mg daily for 6 weeks.
Several studies have suggested that citicoline is effective in treatment of central nervous system disorders (CNS), including acute and chronic cerebral ischemia, intracerebral hemorrhage, global cerebral hypoxia, and neurodegenerative diseases (Martynov 2015).
The intramuscular dose of Citicoline or placebo was added to their hypotensive treatment, followed by a washout period. The Citicoline-treated group showed an improvement of VEP and ERGp parameters when compared to placebo that was treatment-dependent.
8 Νοε 2023 · Citicoline is a naturally occurring brain chemical with neuroprotective properties. It’s also available as a dietary supplement. Learn about its uses, benefits, and potential side effects.
16 Δεκ 2010 · Citicoline safety was excellent; only 37 side effects were observed in 31 patients (0.73%). The most frequent were headache (n=3), gastrointestinal symptoms (n=5), systemic bleeding (n=4), and stroke-related complications (n=8).