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4 Απρ 2022 · The following are the five different classes of antibodies; Immunoglobulin G (IgG) IgG is the most abundant immunoglobin, which accounts for about 80% of the total serum antibodies.
23 Ιαν 2024 · Classes/Types of Antibody. Serum containing antigen-specific antibodies is called antiserum. The 5 types – IgG, IgM, IgA, IgD, IgE – (isotypes) are classified according to the type of heavy chain constant region, and are distributed and function differently in the body. Functions of Antibody.
17 Ιουλ 2023 · Classification. Antibodies are classified according to heavy chain type, which is encoded by a gene on chromosome 14. The different classes are IgG, IgA, IgM, IgD and IgE; in descending order of abundance in serum. IgG. IgG is the most abundant antibody class. It is present on the surface of mature B-cells and in serum.
There are 5 classes of immunoglobulins IgG, IgA, IgM, IgE, and IgD as determined by the presence of unique amino acid sequences in the heavy chain constant regions. The basic structural properties of these immunoglobulin classes are discussed here briefly.
An antibody (formally called immunoglobulin) is a large Y-shaped glycoprotein produced by B-cells and used by the immune system to identify and neutralize pathogens. Antibodies are produced by B cells, and are either secreted into circulation or remain expressed on the surface of the B cell.
There are five main heavy-chain classes or isotypes, some of which have several subtypes, and these determine the functional activity of an antibody molecule. The five major classes of immunoglobulin are immunoglobulin M (IgM), immunoglobulin D (IgD), immunoglobulin G (IgG), immunoglobulin A (IgA), and immunoglobulin E (IgE).
Antibodies are classified into subclasses based on minor differences in the heavy chain type of each Ig class. In humans there are four subclasses of IgG: IgG1, IgG2, IgG3, and IgG4 (numbered in order of decreasing concentration in serum).
