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In patients with atrial fibrillation, clopidogrel should be given as a single daily dose of 75 mg. ASA (75-100 mg daily) should be initiated and continued in combination with clopidogrel (see section 5.1).
In patients with atrial fibrillation, clopidogrel should be given as a single daily dose of 75 mg. ASA (75-100 mg daily) should be initiated and continued in combination with clopidogrel (see section 5.1).
For patients with ST-segment elevation acute myocardial infarction, the recommended dose of clopidogrel is 75 mg once daily, administered in combination with ASA, with or without thrombolytics. Clopidogrel may be initiated with or without a loading dose (300 mg was used in CLARITY).
Plavix is taken once a day as a 75 mg tablet. Use of a loading dose (an initial higher dose) and the duration of treatment depend on the age of the patient and the disease being treated.
DOSAGE AND ADMINISTRATION. Acute coronary syndrome (2.1) Initiate Plavix with a single 300-mg oral loading dose and then continue at 75 mg once daily. Initiating Plavix without a loading dose will delay establishment of an antiplatelet effect by several days.
Generally, clopidogrel should be given as a single daily dose of 75 mg. In patients with acute coronary syndrome: • unstable angina or non-ST elevation myocardial infarction clopidogrel– treatment should be initiated with a single 300 mg loading dose and then continued long- term at 75 mg once a day (with aspirin 75 mg-325 mg daily).
For all other indications, the dose is 75 mg once daily. When switching from ticagrelor to clopidogrel, a loading dose of 300-600 mg should be considered in the early post-ACS period; otherwise, switching directly to 75 mg daily is recommended.
