Αποτελέσματα Αναζήτησης
1 Ιαν 2018 · Characterization of coagulase-negative staphylococcal isolates from blood with reduced susceptibility to glycopeptides and therapeutic options
- Coagulase-Positive and Coagulase-Negative Staphylococci in Human Disease
Staphylococci continue to be the leading cause of many human...
- A Study of The Enterotoxigenicity of Coagulase-Negative and Coagulase-Positive Staphylococcal Isolates From Food Poisoning Outbreaks in Minas Gerais, Brazil
From the pool of 152 staphylococcal isolates, 15...
- A Multinational Population-Based Surveillance Study
Background. Staphylococcus aureus is the second most common...
- The Role of Virulence Determinants in Community-Associated MRSA Pathogenesis
The recent emergence of community-associated...
- Genetic Portraits of Methicillin-Resistant Staphylococcus Aureus Clones
Methicillin-resistant Staphylococcus aureus (MRSA) emerged...
- Endophthalmitis
Coagulase-negative staphylococci are the most common causes...
- By Staphylococcus Hyicus
Five strains of Staphylococcus hyicus (3 of subspecies...
- The Role of Hypervirulent Staphylococcus Aureus Infections in The Development of Deep Vein Thrombosis
S aureus can activate coagulation. In 1994 Patti et al....
- Coagulase-Positive and Coagulase-Negative Staphylococci in Human Disease
One of the hallmarks of S. aureus is its ability to coagulate blood , allowing for clinical differentiation of S. aureus from coagulase-negative Staphylococci (CoNS) such as S. epidermidis . S. aureus secretes two soluble coagulases that interact with prothrombin to catalyze conversion of fibrinogen to fibrin ( McAdow et al., 2012b ).
The coagulase-positive staphylococci constitute the most pathogenic species S aureus. The coagulase-negative staphylococci (CNS) are now known to comprise over 30 other species. The CNS are common commensals of skin, although some species can cause infections.
S. aureus secretes two proteins that promote coagulation, coagulase (Coa) and von Willebrand factor binding protein (vWbp). Both of these proteins activate prothrombin nonproteolytically [ 26 , 27 ].
Results. Compared to the conventional microbiology testing the real‐time PCR assay had a higher detection rate for both S. aureus and coagulase‐negative Staphylococci (CoNS; 55 vs. 32 for S. aureus and 63 vs. 24 for CoNS). Hands‐on time preparing DNA, carrying out the PCR, and evaluating results was less than 5 h. Conclusions.
5 Αυγ 2010 · Clinical isolates of the human pathogen Staphylococcus aureus secrete coagulase (Coa), a polypeptide that binds to and activates prothrombin, thereby converting fibrinogen to fibrin and promoting clotting of plasma or blood. Another secreted coagulase, designated von-Willebrand factor binding protein (vWbp), catalyzes a similar reaction.
1 Ιαν 2018 · Staphylococcal coagulases (Coa, vWbp) are secretory proteins that cause blood clotting through the activation of prothrombin. Based on their ability to clot plasma staphylococci, they may be divided into coagulase-positive or coagulase-negative ones.
