Αποτελέσματα Αναζήτησης
Bacteria in the genus Staphylococcus are pathogens of man and other mammals. Traditionally they were divided into two groups on the basis of their ability to clot blood plasma (the coagulase reaction). The coagulase-positive staphylococci constitute the most pathogenic species S aureus.
S. aureus uses coagulase to form a fibrin coat from fibrinogen present in the bloodstream. This helps the bacteria evade detection and phagocytosis by the immune system. Coagulase is a protein enzyme produced by several microorganisms that enables the conversion of fibrinogen to fibrin.
Keywords: Staphylococcus aureus, clumping, agglutination, fibrinogen, coagulation. 1. Introduction. The gram-positive bacterium Staphylococcus aureus is a common human commensal, colonizing the nostrils and skin of ~30% of the population (Gorwitz et al., 2008; Miller and Diep, 2008).
Clinical isolates of Staphylococcus aureus secrete coagulases, polypeptides that bind to and activate prothrombin, thereby converting fibrinogen to fibrin and promoting the clotting of plasma or blood. Two staphylococcal products, the canonical ...
17 Ιουλ 2023 · Staphylococcus aureus is Gram-positive bacteria (stain purple by Gram stain) that are cocci-shaped and tend to be arranged in clusters that are described as “grape-like.” On media, these organisms can grow in up to 10% salt, and colonies are often golden or yellow (aureus means golden or yellow).
1 Ιαν 2018 · Introduction. Staphylococci are Gram-positive, commensal components of human and animal cutaneous and mucosal microflora. They are also leading causes of numerous skin, tissue, as well as systemic infections that are sometimes serious.
The ability of coagulase to stimulate clot formation in plasma is a defining property of S. aureus that has been known for over 100 years [1]. It provides a simple and widely used test to identify S. aureus and distinguish it from the less virulent ‘coagulase-negative’ staphylococci.
