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8 Νοε 2023 · Cobalt was widely used for hip and knee joint replacements until cases of heavy metal poisoning appeared. Now, researchers from the University of Connecticut School of Medicine and Carnegie Mellon report a way to protect people with these implants from cobalt toxicity.
1 Μαρ 2022 · Whereas cobalt exposure is possibly greater in patients implanted with MoM articulating devices, patients implanted with other forms of articulating devices (eg, MoP) are also potentially exposed to cobalt chromium alloy from components in the joint replacement (Eltit et al., 2019). Total knee replacement implants are also metal-based and ...
2 Φεβ 2024 · In the absence of a readily available current summation, this paper aimed to review the current literature regarding in situ allergy to cobalt and/or chromium metals when used as substrates within modern joint replacements and to summarize the evidence underpinning such diagnosis.
19 Αυγ 2021 · Patients with a suspected hip, knee, or shoulder replacement containing cobalt-chrome were screened with a spot screening of cobalt in urine. Levels of cobalt in blood were then determined for patients with cobalt levels in urine 1 ppb or higher.
15 Ιουλ 2021 · The incidence of raised cobalt and chromium levels after total knee replacement (TKR) is relatively unknown but it does exist in the presence of loose knee implants and further research is required. A revision of TKR was required for the management of the case.
20 Σεπ 2020 · In recent years, increasing concern has been raised regarding potential systemic toxicity of metals released from arthroplasty implants. A lack of valid metal thresholds for human (organ) toxicity and the prospect of multi-decade survival of modern hip and knee replacements pose special challenges. …
Systemic cobalt (Co) and chromium (Cr) concentrations may be elevated in patients with metal joint replacement prostheses. ... Cr 3+ concentrations, and has the potential to serve as early markers of metal toxicity. Finally, our study provides a molecular basis for the improved clinical outcomes for hydroxyapatite-coated prostheses that elicit ...
