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1. Introduction. Chronic obstructive pulmonary disease (COPD) is an important public health issue in both developed and developing countries. It is an important preventable and treatable disease and poses a heavy socioeconomic burden due to its high morbidity and mortality.[] COPD is the third most common cause of death in the world, according to the World Health Organization (WHO).[]
Most patients who are hospitalized with an exacerbation of COPD should be treated with systemic corticosteroids, unless side-effects are limiting [I, A]. A dose of prednisone, 40 mg orally daily, for a 5-day course, is appropriate for most patients, and a dose taper is unnecessary ( Table 3 ) [I, A].
Provide a framework for management of chronic COPD and for the treatment of mild to moderate acute exacerbations. Improve symptoms, quality of life and lung function while reducing morbidity and mortality for patients with COPD. Key points.
The participants included adults who were likely to have COPD based on clinical diagnosis, spirometry, or known or suspected history; the individuals must have been experiencing an acute exacerbation of respiratory symptoms.
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: 2023 report. 2023 [internet publication]. https://goldcopd.org/2023-gold-report-2. Give oral antibiotics first-line if possible and if the severity of the exacerbation does not require intravenous antibiotics. [1]
In addition, the paper provides recommendations related to non-invasive ventilation treatment and home-based management, and is centred on six key questions: Oral corticosteroids versus. no corticosteroids for non-hospitalised patients. Oral corticosteroids vs. intravenous corticosteroids for hospitalised patients.
12 Ιουλ 2024 · The Global Initiative for Chronic Obstructive Lung Disease (GOLD), a report produced by the National Heart, Lung, and Blood Institute (NHLBI) and the World Health Organization (WHO), defines an exacerbation of chronic obstructive pulmonary disease (COPD) as "an event characterized by dyspnea and/or cough and sputum that worsens over ≤14 days, wh...
