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  1. 1. Introduction. Chronic obstructive pulmonary disease (COPD) is an important public health issue in both developed and developing countries. It is an important preventable and treatable disease and poses a heavy socioeconomic burden due to its high morbidity and mortality.[] COPD is the third most common cause of death in the world, according to the World Health Organization (WHO).[]

  2. Most patients who are hospitalized with an exacerbation of COPD should be treated with systemic corticosteroids, unless side-effects are limiting [I, A]. A dose of prednisone, 40 mg orally daily, for a 5-day course, is appropriate for most patients, and a dose taper is unnecessary (Table 3) [I, A]. Antibiotics.

  3. The Task Force provided recommendations related to corticosteroid therapy, antibiotic therapy, noninvasive mechanical ventilation, home-based management, and early pulmonary rehabilitation in patients having a COPD exacerbation. These recommendations should be reconsidered as new evidence becomes available. Copyright ©ERS 2017. Introduction.

  4. 26 Αυγ 2020 · For the management of acute exacerbations of chronic obstructive pulmonary disease (AECOPD), a combination of a short-acting β2 agonist (SABA) and a short-acting muscarinic antagonist (SAMA) is recommended to alleviate exacerbation symptoms. 1, 2 These medications should be administered via a metered dose inhaler (MDI) with a spacing chamber dev...

  5. 2 Οκτ 2018 · Patients with chronic obstructive pulmonary disease (COPD) may experience an acute worsening of respiratory symptoms that results in additional therapy; this event is defined as a COPD exacerbation (AECOPD).

  6. In adult patients with exacerbations of COPD, what are the benefits and harms of combinations of treatments that are individually effective (based on empirical evidence in stable COPD)? Key ...

  7. 12 Ιουλ 2024 · The Global Initiative for Chronic Obstructive Lung Disease (GOLD), a report produced by the National Heart, Lung, and Blood Institute (NHLBI) and the World Health Organization (WHO), defines an exacerbation of chronic obstructive pulmonary disease (COPD) as "an event characterized by dyspnea and/or cough and sputum that worsens over ≤14 days, wh...

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