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This review aims to discuss the role of dietary sugar in NAFLD pathogenesis, the health and economic burden, and the promising potential of sugar reduction to improve health outcomes for patients with this chronic liver disease.
If we eat sugar on a regular basis, the chemicals build up in our bodies affecting our liver and some other internal organs, which can eventually lead to liver damage. When the liver is damaged, fatty or inflamed, it can’t work as efficiently as a healthy liver.
It is now generally thought that increased consumption of added sugar, in particular fructose sweeteners, 3–6 is one of the major underlying causes of chronic metabolic diseases, including obesity, insulin resistance, non-alcoholic fatty liver disease (NAFLD), diabetes, and cardiovascular diseases. 7– 12 In this review, we will focus on the effe...
19 Μαρ 2021 · Consuming moderate amounts of specific types of sugar may double the production of fat in the liver. This in turn can lead to the development of fatty liver disease and type 2 diabetes.
10 Δεκ 2021 · Here, we reviewed the different dietary sugar types, their metabolism, and the effects of excessive intake on intestinal homeostasis, the gut microbiota, and gastrointestinal diseases.
6 Νοε 2023 · This review aims to discuss the role of dietary sugar in NAFLD pathogenesis, the health and economic burden, and the promising potential of sugar reduction to improve health outcomes for patients with this chronic liver disease.
NAFLD is predicted to be the most common cause of liver transplantation by 2030 (Byrne and Targher, 2015 [8]). NAFLD increases overall mortality by 57 % and doubles the risk of type 2 diabetes (Musso et al., 2011 [34]) and chronic kidney disease (CKD) (Musso et al., 2014 [35]).
