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This review aims to discuss the role of dietary sugar in NAFLD pathogenesis, the health and economic burden, and the promising potential of sugar reduction to improve health outcomes for patients with this chronic liver disease.
If we eat sugar on a regular basis, the chemicals build up in our bodies affecting our liver and some other internal organs, which can eventually lead to liver damage. When the liver is damaged, fatty or inflamed, it can’t work as efficiently as a healthy liver.
In summary, there has been a marked rise in sugar and HFCS intake that has paralleled the rise of NAFLD. Experimentally, the fructose component of sugar and HFCS appears to have a major role in inducing fatty liver by both stimulating de novo lipogenesis and blocking β-fatty acid oxidation.
In summary, the actions and possible detrimental effects of high fructose on the liver are concerning, especially with the rise in consumption of sweeteners such as HFCS and sucrose. Its contributions to NAFLD and NASH have been supported by numerous studies, and can be explained by multiple mechanisms.
19 Μαρ 2021 · Consuming moderate amounts of specific types of sugar may double the production of fat in the liver. This in turn can lead to the development of fatty liver disease and type 2 diabetes.
8 Αυγ 2023 · Fifth, sugar-sweetened beverage–associated metabolites such as taurine and phenylalanine were associated with hepatocellular carcinoma. 34,35 Sixth, added sugar from liquid sources, such as soft soda and fruit drinks, is rapidly absorbed, which might lead to metabolic conditions and liver problems. 36 Seventh, chemicals contained in these ...
10 Δεκ 2021 · Both hyperglycemia and excessive sugar intake disrupt the intestinal barrier, thus increasing gut permeability and causing profound gut microbiota dysbiosis, which results in a disturbance in mucosal immunity that enhances infection susceptibility.
