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In mammals, the sex chromosomes are called X and Y. Females have paired X chromosomes, one from each parent, while males have an X and a Y chromosome. Males get their single X chromosome only from their mothers and their Y chromosome only from their fathers.
In the XY sex-determination system, the female-provided ovum contributes an X chromosome and the male-provided sperm contributes either an X chromosome or a Y chromosome, resulting in female (XX) or male (XY) offspring, respectively.
In contrast, the X and Y chromosome synapse only in the short homologous pseudoautosomal regions, and form the so-called XY body. 1 In this specialized chromatin area, transcription is shut down by a mechanism named meiotic sex chromosome inactivation (MSCI) (reviewed by Refs. 2 and 3). The sex chromosomes remain silent throughout the rest of ...
14 Οκτ 2022 · Representations of the human X and Y chromosomes (generalizable to all eutherian mammals) are presented in the center, showing the pseudoautosomal regions (PAR1 and PAR2) at the distal ends, the non-PAR of the X, the male specific region of the Y (MSY) and the Sry gene position.
16 Ιουλ 2021 · The human sex chromosomes, called X and Y, are structures in human cells made up of tightly bound deoxyribonucleic acid, or DNA, and proteins. Those are molecules that contain the instructions for the development and functioning of all life forms, including the development of physical traits and body parts that correspond with each biological sex.
27 Μαΐ 2020 · Early pachynema was defined as complete autosomal synapsis, whereas the X and Y chromosomes could display various configuration: i) unsynapsed, with thickened PAR axes; ii) engaged in PAR...
1 Ιαν 2023 · In this review, we discuss the changes in chromatin conformation taking place between somatic and meiotic cells, with a special focus on the establishment of a proteinaceous structure, called the chromosome axis, at the beginning of meiosis.
