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  1. 5 Οκτ 2024 · Type 1 diabetes mellitus (T1DM) is an autoimmune disease that leads to the destruction of insulin-producing pancreatic beta cells. Insulin is an essential anabolic hormone that exerts multiple effects on glucose, lipid, protein, mineral metabolism, and growth.

  2. 13 Οκτ 2020 · Diabetes follows a progressive pattern with complex pathogenesis and varied presentation. [1, 2] Hyperglycemia and its associated carbohydrate, fat, and protein metabolic dysfunctions affect multiple organs of the body and disrupt their normal functioning.

  3. 5 Οκτ 2024 · Identify the pathophysiological mechanisms underlying type 1 diabetes, including the role of autoimmune processes and genetic factors, to better inform diagnosis and treatment strategies. Implement the latest advancements in diabetes technology to optimize glycemic control.

  4. 7 Φεβ 2023 · Classical Type 1 Diabetes Mellitus Pathoetiology. T1DM arises from the dysregulation of pancreatic β-cell insulin production and insulin effects. Pancreatic β-cell function and insulin release are intimately linked to variations in blood glucose.

  5. 28 Ιουν 2019 · This chapter reviews the etiopathogenesis of type 1 diabetes, which includes genetic (such as a strong association with HLA haplotypes, genetic linkage with immune system genes), immunological (such as specificity for beta cells and the presence of antigen-specific T...

  6. 30 Μαρ 2017 · Abstract. Type 1 diabetes mellitus (T1DM), also known as autoimmune diabetes, is a chronic disease characterized by insulin deficiency due to pancreatic β-cell loss and leads to...

  7. 3 Μαρ 2023 · Type 1 diabetes mellitus (T1DM) is an autoimmune disease that leads to the destruction of insulin-producing pancreatic beta cells. Insulin is an essential anabolic hormone that exerts multiple effects on glucose, lipid, protein, mineral metabolism, and growth.

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