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  1. 15 Αυγ 2022 · 23 studies were included, reporting 505,390 diabetes-related lower extremity amputations. IR of minor amputations was 139.97 (95% CI 88.18–222.16) per 100,000 individuals with diabetes, among patients with type 1 diabetes was 148.59 (95% CI 65.00–339.68) and in type 2 diabetes was 75.53 (95% CI 29.94–190.54).

  2. 25 Ιουν 2020 · Diabetes mellitus is known to increase the incidence of PAD, accelerate disease progression, and increase disease severity. Patients with concomitant diabetes mellitus and PAD are at high risk for major complications, such as amputation.

  3. 22 Αυγ 2022 · Patients with diabetes mellitus have an astounding 30 times greater lifetime risk of undergoing an amputation when compared to patients without diabetes mellitus, which translates to an economic strain in healthcare systems of over $4.3 billion in annual costs in the USA alone.

  4. IR estimates of diabetes-related amputations with associated 95% confidence interval (CI) per 100,000 individuals with diabetes were calculated. Results: 23 studies were included, reporting 505,390 diabetes-related lower extremity amputations.

  5. The incidence of lower extremity reamputation is high among patients with diabetes who have undergone initial amputations secondary to diabetes, and rates of reamputation have not changed over at least two decades.

  6. RESULTS. 2.3 per 1,000 patients underwent a major amputation from 2007–2011, with the higher rate among black patients (5.5 per 1,000 versus 1.9 per 1,000, p<0.001) compared to non-black. The rate varied widely by HRR (1.2 per 1,000 to 6.2 per 1,000), with higher variation in amputation rates in black patients (2.1 to 16.1 per 1,000).

  7. Close to 140 000 diabetes-related amputations occur every year in the USA and structural inequality leads to Black people being four times more likely to have an amputation than white people. Low rates of angiogram screening for nerve damage and PAD result in many unnecessary amputations.

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