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Stage 1 is characterized by decreased bone marrow iron stores; hemoglobin (Hb) and serum iron remain normal, but the serum ferritin level falls to < 30 ng/mL (< 67.4 pmol/L). The compensatory increase in iron absorption causes an increase in iron-binding capacity (transferrin level).
- Megaloblastic Macrocytic Anemias
It should also be considered in patients with risk factors...
- Anemia of Chronic Disease
Diagnosis generally requires the presence of a chronic...
- Myelophthisic Anemia
Myelophthisic anemia is a normocytic, normochromic anemia...
- Megaloblastic Macrocytic Anemias
15 Ιαν 2013 · The diagnosis of iron deficiency anemia is confirmed by the findings of low iron stores and a hemoglobin level two standard deviations below normal. Women should be screened during pregnancy, and...
4 Ιαν 2022 · Hemoglobin. Lower than normal hemoglobin levels indicate anemia. The normal hemoglobin range is generally defined as 13.2 to 16.6 grams (g) of hemoglobin per deciliter (dL) of blood for men and 11.6 to 15 grams (g) of hemoglobin per deciliter (dL) of blood for women. Ferritin.
10 Σεπ 2024 · The diagnosis of iron deficiency (low iron stores, as measured by iron studies or other testing) is a major public health goal and an important aspect of the care of many adults. This topic will review the causes of iron deficiency in adults and an approach to the diagnostic evaluation.
6 Δεκ 2019 · Serum ferritin is the most reliable initial test for diagnosing absolute ID. 15 Ferritin is an intracellular iron storage protein that correlates with the body’s iron stores in the absence of inflammation.
The normal range is 15 – 300 µg/dL. The sensitivity and specificity of the test vary depending on cut-off levels used to define iron deficiency; at a cut-off level of 15µg/L, the test is highly specific for iron deficiency, but lacks sensitivity. At a cur-off level of 100µg/L, the sensitivity increases to 94%, at the expense of specificity (71%).
15 Ιουλ 2024 · Transferrin saturation (e.g., less than 15% in adult and less than 7% in pediatric subjects) helps define low plasma iron availability to tissues in both absolute and functional ID in adult subjects. Soluble transferrin receptor (sTfR) is an index of tissue iron needs and of erythropoietic activity.
