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4 Δεκ 2020 · Ferritin <30 μg/L in the presence of TSAT <45% is indicative of absolute low iron stores (black). Most patients with CICs in association with true ID are found to have TSAT<20% and ferritin <200 μg/L (red).
6 Δεκ 2019 · Serum ferritin is the most reliable initial test for diagnosing absolute ID. 15 Ferritin is an intracellular iron storage protein that correlates with the body’s iron stores in the absence of inflammation.
Iron studies diagnostic for iron deficiency anemia consist of a low hemoglobin (<7.7 mmol/l in men and 7.4 mmol/l in women), a low serum iron (<7.1 µg/l), a low serum ferritin (storage form of iron) (<30 ng/l), a low transferrin saturation (<15%), and a high total iron-binding capacity (>13.1 µmol/l) [Bermejo and Garcia-Lopez, 2009; Clark, 2009].
3 Ιαν 2019 · The diagnosis of absolute iron deficiency is easy unless the condition is masked by inflammatory conditions. All cases of iron deficiency should be assessed for treatment and underlying cause. Special attention is needed in areas endemic for malaria and other infections to avoid worsening of infection by iron treatment.
15 Ιουλ 2024 · Transferrin saturation (e.g., less than 15% in adult and less than 7% in pediatric subjects) helps define low plasma iron availability to tissues in both absolute and functional ID in adult subjects. Soluble transferrin receptor (sTfR) is an index of tissue iron needs and of erythropoietic activity.
Red blood cells tend to be microcytic and hypochromic, and iron stores are low, as shown by low serum ferritin and low serum iron levels with high serum total iron-binding capacity. Once the diagnosis is made, occult blood loss should be suspected until proven otherwise.
9 Ιαν 2023 · Abstract. Iron deficiency (ID) is the most common nutritional disorder worldwide. It is often observed in patients with chronic diseases, such as heart failure (HF), chronic kidney disease (CKD), inflammatory bowel disease (IBD) and cancer.
