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  1. 16 Οκτ 2019 · How evolution builds genes from scratch. Scientists long assumed that new genes appear when evolution tinkers with old ones. It turns out that natural selection is much more creative. By....

  2. 9 Μαρ 2022 · A framework for studying and engineering gene regulatory DNA sequences, based on deep neural sequence-to-expression models trained on large-scale libraries of random DNA, provides insight into...

  3. 18 Απρ 2016 · The authors review the mechanisms by which gene loss has influenced evolution of different species and discuss insights from comparative population genomics studies of gene loss.

  4. 14 Φεβ 2020 · Altogether, we analysed 608 genes in 592 cases and 560 controls and identified four genes as strongly associated (one genome-wide). Two of these genes, NRXN1 and HTR2A, were enriched for protein-coding mutations in cases, while two genes, CTTNBP2 (synapse maintenance) and REEP3 (vesicle trafficking), had only regulatory mutations in this study ...

  5. 29 Φεβ 2024 · Growing evidence from archaic and early modern human genomes brings new insights to the emergence of modern humans. We recount recent information collected from ancient DNA studies that inform us about the evolutionary pathway to modern humanity.

  6. 24 Ιαν 2014 · With improved capacity to screen large numbers of samples for those with high proportions of endogenous ancient DNA, paleogenomics is poised to become a key technology to better understand recent evolutionary events.

  7. 25 Ιαν 2024 · report the establishment of an orthogonal DNA replication system in Escherichia coli (EcORep) that will allow in vivo rapid continuous directed evolution of RNAs, enzymes, proteins, and genetic circuits toward new activities.

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