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24 Σεπ 2018 · To understand the structure and chemistry of DNA and the significance of the double helix. Objectives. After this chapter, you should be able to. explain the structural basis for the directionality of polynucleotide chains. describe how hydrogen bonding and geometry dictate base pairing. describe the forces that stabilize the DNA double helix.
21 Απρ 2015 · The proposal of a double-helical structure for DNA over 60 years ago provided an eminently satisfying explanation for the heritability of genetic information. But why is DNA, and not RNA, now...
DNA structure. DNA is made up of molecules called nucleotides. Each nucleotide contains a phosphate group, a sugar group and a nitrogen base. The four types of nitrogen bases are adenine (A), thymine (T), guanine (G) and cytosine (C). The order of these bases is what determines DNA's instructions, or genetic code.
DNA SEQUENCING AND GENE STRUCTURE. Nobel lecture, 8 December, 1980. by. WALTER GILBERT. Harvard University, The Biological Laboratories, Cambridge, Massachusetts. 02138, USA. When we work out the structure of DNA molecules, we examine the fundamen-tal level that underlies all process in living cells.
DNA structure and function. I. Introduction. - DNA holds the genetic information of a cell -- heritable information. II. DNA structure. a polymer of nucleotides -- two strands of nucleotides twisted around each other in a double helix, held together by hydrogen bonds. three types of nucleotides.
One of the fundamental things to know when studying genetics is the basic structure of DNA and how it is replicated. DNA is the “blueprint” that contains all the instructions for making the proteins that each cell needs, whether it is a single celled bacterium or a multicellular organism like humans. J.
What to Sequence and Why? Structure. Function. De novo whole genome sequencing. requires de novo whole genome assembly. Polymorphism discovery. (distinct from genotyping) Targeted approaches (exome) Whole genome. SNPs, copy number variations, insertions, deletions, etc. Expressed sequence discovery and functional genomics.
