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15 Φεβ 2024 · These findings are often associated with various conditions, including Infectious Mononucleosis (IM) due to Epstein-Barr virus (EBV) infection, as well as other infectious and non-infectious causes. Downey type1 cells are smaller in size, have indented to lobulated nucleus and cytoplasmic granules.
- Reactive lymphocyte - American Society of Hematology
These cells are also called Downey type II cells. They can...
- Infectious mononucleosis - 3. - American Society of Hematology
A classical Downey cell is shown with abundant muddy...
- Reactive lymphocyte - American Society of Hematology
1 Μαρ 2016 · These cells are also called Downey type II cells. They can be seen in a variety of conditions, but are often increased in infectious mononucleosis due to EBV infection. Download Image
18 Ιαν 2020 · In 1923, McKinlay and Downey published a description of three types of reactive or atypical lymphocytes, which they called Downey cells. The presence of many of these cells became the standard laboratory test for infectious mononucleosis.
1 Μαρ 2010 · A classical Downey cell is shown with abundant muddy basophilic cytoplasm and vacuolization.
Clinical Picture. Infectious mononucleosis diagnosed by Downey cells: sometimes the old ways are better. Henry M Feder Jr, William N Rezuke. An 18-year-old woman visited her physician because she had a fever, a sore throat, and painful swellings in her neck for the past 5 days.
In immunology, reactive lymphocytes, variant lymphocytes, atypical lymphocytes, Downey cells or Türk cells are cytotoxic (CD8 +) lymphocytes that become large as a result of antigen stimulation. Typically, they can be more than 30 μm in diameter with varying size and shape.
Infectious mononucleosis is a clinical entity characterized by sore throat, cervical lymph node enlargement, fatigue and fever most often seen in adolescents and young adults and lasting several weeks. It can be caused by a number of pathogens, but ...